Physical restraint is defined by the Guide as “The use of manual or mechanical means to limit some or all of an animal’s normal movement for the purpose of examination, collection of samples, drug administration, therapy, or experimental manipulation.” Methods of restraint must be described in the animal use protocol and approved by the IACUC.
Examples of physical restraint include:
- Restraint chambers or devices
- Unconventional tethering - tethering that suspends the rear legs above the cage floor or short tethering that actually restricts movement
- Large animal stanchions