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Guidelines
Oct 20, 2023

End-Stage Illness Scoring System

To establish a guideline for an end-stage illness scoring system to be used for animals displaying severe signs of morbidity, or a moribund state. This guideline does not replace use of common sense and empathy to protect animals from avoidable...
Guidelines
Oct 20, 2023

Guidelines on Experimental Food or Water Restriction or Manipulation in Laboratory Animals

Food and water restriction can be an important and commonly used research tool in many experimental studies. This restriction has the potential to adversely affect an animal's well-being. In keeping within federal and university guidelines, and...
Guidelines
Oct 6, 2023

University of Michigan Euthanasia Guidelines

These guidelines are based on the AVMA Guidelines for the Euthanasia of Animals (2020 Edition) . Abbreviation codes are as follows: A = Acceptable - those which consistently produce a humane death when used as the sole means of euthanasia AC =...
Guidelines
Sep 18, 2023

Guidelines on the Preparation of Injectable Substances and Agents Administered to Animals

This guideline outlines the expectations for the preparation of injectable substances and agents intended for use in animals.
Guidelines
Aug 25, 2023

Anesthesia and Sedation Monitoring Guidelines

This document was created by the ULAM veterinary staff as a guideline for anesthesia and sedation monitoring. This is not intended to be an inclusive tutorial on all possible methods and all equipment available for anesthesia monitoring. Detailed...
Guidelines
Aug 25, 2023

Guidelines on the Performance of Surgery in Rodents

This document is intended to provide guidelines for investigators who perform surgical procedure(s) in rodents such as mice, rats, hamsters, gerbils, guinea pigs, etc. All surgical procedures, anesthetics, analgesics, antibiotics or other...
Guidelines
Jul 28, 2023

Evaluation of Alopecia in Non-Human Primates

Alopecia is a common problem in captive, non-human primates (NHP). Alopecia is manifested as hair loss without any clinical changes at the skin surface. This condition can be a result of various causes including clinical, environmental, or...
Guidelines
Jul 28, 2023

Guidelines for Rodent Euthanasia Procedures for Investigative Personnel

To establish acceptable methods of euthanasia for investigative personnel to perform. The current procedure is composed of two parts: a primary method followed by a secondary method to ensure death and/or prevent revival.
Guidelines
Jun 2, 2023

Guidelines on Anesthesia and Analgesia in Ruminants

This set of guidelines was prepared by the ULAM veterinary staff to provide general recommendations for anesthesia and analgesia in laboratory ruminants. This is not intended to be an all-inclusive tutorial, and does not factor in specific research-...
Guidelines
May 19, 2023

Guidelines on Anesthesia and Analgesia in Rats

This document has been designed by the ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory rats. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in rats...
Guidelines
May 19, 2023

Guidelines on Reptile Anesthesia Analgesia and Surgery

This document has been designed by ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory reptiles. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in...
Guidelines
May 19, 2023

Guidelines on Anesthesia and Analgesia in Mice

This document has been designed by the ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory mice. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in mice...
Guidelines
Mar 10, 2023

Guidelines on Fish Anesthesia Analgesia and Surgery

This document has been designed by ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of laboratory fish. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in fish...
Guidelines
Mar 10, 2023

Guidelines on Amphibian Anesthesia Analgesia and Surgery

This document has been designed by ULAM veterinary personnel as a guideline for sedation , anesthesia , and analgesia of amphibians, specifically Xenopus sp. This is not intended to be an inclusive tutorial on all possible drug combinations that can...
Guidelines
Jan 27, 2023

Physical Exams for Aging Rabbits

Additional procedures associated with older rabbits.
Guidelines
Oct 21, 2022

Guidelines for Acceptable Methods of Identification and Genotyping of Rodents and Zebrafish

To describe procedures to safely and appropriately identify and genotype animals used in laboratory research at the University of Michigan.
Guidelines
Aug 12, 2022

Guidelines for Documenting Justification for Exceeding Cage Densities

The Guide defines the maximum number of rodents allowed in a given cage space and is the regulatory source for the Guidelines on Mouse and Rat Breeding and Housing Management . This document is intended to provide guidelines for investigators who...
Guidelines
Aug 12, 2022

Guidelines on Mouse and Rat Breeding and Housing Management

To address the health and well-being of mice and rats by ensuring safe breeding practices and population densities. Limiting breeding cage occupancy reduces the incidence of morbidity and mortality due to overcrowding. In all cases, cages should be...
Guidelines
Sep 8, 2021

Guidelines on Administration of Substances to Laboratory Animals

This document is designed to provide general guidelines about administration of substances to laboratory animals. All procedures must be approved by the Institutional Animal Care & Use Committee (IACUC). The route of administration, intervals...
Guidelines
Apr 23, 2021

Guidelines on Blood Collection

This document is designed to provide general information on blood collection methods for common laboratory animals. All procedures must be approved by the Institutional Animal Care and Use Committee (IACUC). The method of blood collection to be used...

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GUIDANCE & OVERSIGHT
Animal Care & Use Office (ACUO)
2800 Plymouth Road
Ann Arbor, MI 48109
Phone: (734) 763-8028
Email: acuoffice@umich.edu

HUSBANDRY & VETERINARY CARE
Unit for Laboratory Animal Medicine (ULAM)
2800 Plymouth Road
Ann Arbor, MI 48109
Phone: (734) 764-0277
Email: ulam-questions@umich.edu

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