{"id":2973,"date":"2024-11-04T12:56:19","date_gmt":"2024-11-04T12:56:19","guid":{"rendered":"https:\/\/az.research.umich.edu\/animalcare\/document\/anesthesia-and-sedation-monitoring-guidelines\/"},"modified":"2025-02-17T14:46:25","modified_gmt":"2025-02-17T14:46:25","slug":"anesthesia-and-sedation-monitoring-guidelines","status":"publish","type":"document","link":"https:\/\/az.research.umich.edu\/animalcare\/guidelines\/anesthesia-and-sedation-monitoring-guidelines\/","title":{"rendered":"Anesthesia and Sedation Monitoring Guidelines"},"template":"","categories":[5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,37],"tags":[],"content-type":[39],"topic":[34],"update-type":[],"class_list":["post-2973","document","type-document","status-publish","hentry","category-cats","category-chickens-avian","category-cows","category-dogs","category-ferrets","category-fish-amphibians-and-reptiles","category-guinea-pigs","category-hamsters","category-mice","category-other-rodents","category-primates","category-rabbits","category-rats","category-sheep","category-swine","category-usda-other","content-type-guidelines","topic-anesthesia-and-analgesia"],"acf":{"use_legacy_editor":true,"updated_date":"2025-10-17 00:00:00","update_notice":true,"author":"Unit for Laboratory Animal Medicine","summary":"
    \r\n \t
  1. This document was created by the ULAM veterinary staff as a guideline for anesthesia<\/a>\u00a0and sedation<\/a> monitoring. This is not intended to be an inclusive tutorial on all possible methods and all equipment available for anesthesia monitoring.\r\n
      \r\n \t
    1. Find detailed information for species-specific anesthesia and analgesia<\/a>.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
    2. Contact ULAM veterinary staff (ulam-vets@umich.edu<\/a>) and\/or ULAM Training Core (ulam-trainingcore@umich.edu<\/a>) for additional training on these techniques.\r\n
        \r\n \t
      1. If surgical procedures will be performed outside of ULAM-ASOR<\/a>, the ULAM veterinary staff should be contacted for monitoring equipment recommendations.<\/strong><\/li>\r\n \t
      2. If neuromuscular blockade is used, the ULAM veterinary staff will need to be contacted for dosing and monitoring guidance (See Guidelines for the Use of Neuromuscular Blockers<\/a> (Paralytics).<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>","button_links":null,"related_content":[2917,2890,2891],"legacy_path":"anesthesia-and-sedation-monitoring-guidelines","legacy_node_id":123,"legacy_related_nids":"62, 35, 36, 1045, 1044, 1048","legacy_content_section":[{"legacy_section_type":"heading","legacy_heading":"Responsibility","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area","legacy_heading":"","legacy_subheading":"","legacy_section_text":"
          \r\n \t
        1. Principal Investigator: <\/strong>Responsible to ensure appropriate anesthesia, monitoring, and analgesia is provided for all animals undergoing surgical or sedation procedures.<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"heading","legacy_heading":"Glossary Definitions","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"glossary_terms","legacy_heading":"","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":[2404,2405,3326,3325,2690],"legacy_glossary_nids":"1072, 1071, 1371","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"heading","legacy_heading":"Rodent Anesthetic \/ Sedation Expectations","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"1. Rodent Recovery Anesthesia \/ Sedation & Monitoring","legacy_section_text":"
            \r\n \t
          1. Recovery Anesthesia Expectations<\/strong>\r\n
              \r\n \t
            1. Procedures must meet current veterinary anesthesia standards of care.<\/li>\r\n \t
            2. Principal Investigators<\/a> (PIs) are expected to provide anesthesia and monitoring equipment corresponding to the complexity and potential anesthetic complications associated with their research model.<\/li>\r\n \t
            3. Lab personnel are expected to maintain aseptic technique while providing appropriate anesthetic monitoring during surgery and aseptic procedures. This requires careful planning and organization to prevent breaks in sterile technique and facilitate monitoring when one person is serving as both surgeon and anesthetist. When possible, it is recommended to have one person dedicated to the procedure\/surgery and a separate person dedicated to anesthesia monitoring<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
            4. Anesthetic Evaluation<\/strong>\r\n
                \r\n \t
              1. Once the rodent is anesthetized, the anesthetic depth must be evaluated prior to initiating the procedure. Appropriate anesthetic depth is determined by absence of painful response, such as pedal or toe pinch.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
              2. Monitoring<\/strong>\r\n
                  \r\n \t
                1. Do not leave animals unattended during the anesthetic period \u2013 remain within visual contact at all times to facilitate appropriate monitoring.\r\n
                    \r\n \t
                  1. Once the animal is in the recovery period, it is okay to step out of visual contact of the animal as long as:\r\n
                      \r\n \t
                    1. The animal is fully extubated with normal respirations (when applicable)<\/li>\r\n \t
                    2. The animal is fully secured so that if it becomes ambulatory it cannot escape the enclosure it is in (e.g. housing cage with lid)<\/li>\r\n \t
                    3. A visual check occurs at least once every 15 minutes<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                    4. Animals can be returned to a rack housing system once they are fully ambulatory.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                    5. Monitoring is recommended throughout the anesthetic event at minimum every 15 minutes.<\/li>\r\n \t
                    6. Cardiovascular System:\r\n
                        \r\n \t
                      1. Tail, foot, tongue or ear color can be monitored for pale or blue membranes, which is indicative of decreased blood volume, decreased perfusion or respiratory distress.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                      2. Respiratory System:\r\n
                          \r\n \t
                        1. Small rodents have respiratory rates too quick to accurately count. Instead, an assessment of the breathing pattern should be made. (e.g., regular vs. irregular breaths).<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                        2. Body Temperature:\r\n
                            \r\n \t
                          1. Rodents are prone to hyperthermia and hypothermia.\r\n
                              \r\n \t
                            1. Warming devices should provide gentle heat only (maximum of 102\u00b0F). An insulated pad or folded drape must be placed between the animal and the heat source.<\/li>\r\n \t
                            2. AVOID commercial human electric heating pads, and heating lamps. <\/strong><\/span><\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                            3. See Appendix C<\/strong><\/em> for recommended warming devices.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"2. Sedation Without General Anesthesia","legacy_section_text":"
                                \r\n \t
                              1. Cardiovascular, respiratory, and temperature monitoring guidelines should follow recovery anesthesia monitoring guidelines.<\/li>\r\n \t
                              2. Oxygen should be supplemented by facemask.<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"3. Non-Recovery Anesthesia","legacy_section_text":"
                                  \r\n \t
                                1. Pre-Anesthetic Examination<\/strong>\r\n
                                    \r\n \t
                                  1. A physical examination should be performed including heart rate and rhythm, mucous membrane color (normal = pink), capillary refill time (normal < 2 seconds), respiratory sounds and rate, and temperature.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"4. Records","legacy_section_text":"
                                      \r\n \t
                                    1. Monitoring records are recommended for any rodent undergoing any survival procedure<\/a>. Additional required records must be kept for rodents undergoing survival surgery. For more information on medical documentation of procedures and surgical monitoring, please refer to Guidelines on Medical Records for Investigative Personnel <\/a><\/em><\/strong>and Guidelines on the Performance of Surgery in Rodents<\/a><\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"heading","legacy_heading":"Non-Rodent Mammal Anesthesia \/ Sedation Expectations","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"1. Non-Rodent Mammal Recovery Anesthesia & Monitoring","legacy_section_text":"
                                        \r\n \t
                                      1. Recovery Anesthesia Expectations<\/strong>\r\n
                                          \r\n \t
                                        1. Procedures must meet current veterinary anesthesia standards of care.<\/li>\r\n \t
                                        2. Principal Investigators (PIs) are expected to provide anesthesia and monitoring equipment corresponding to the complexity and potential anesthetic complications associated with their research model.<\/li>\r\n \t
                                        3. Lab personnel are expected to maintain aseptic technique while providing appropriate anesthetic monitoring during surgery and aseptic procedures. Typically, this requires one person dedicated to the procedure or surgery and a separate person dedicated to anesthesia monitoring.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                        4. Pre-Anesthesia Evaluation and Anesthetic Depth Assessment<\/strong>\r\n
                                            \r\n \t
                                          1. A physical examination should be performed including: heart rate and rhythm, mucous membrane color (normal = pink), capillary refill time (normal <2 seconds), respiratory sounds and rate, and temperature.\u00a0It is recommended to perform the following baseline clinical chemistries: packed cell volume (PCV) or hematocrit, total protein, glucose, blood urea nitrogen (BUN), and serum creatinine.<\/li>\r\n \t
                                          2. Adequate anesthetic depth must be evaluated prior and during anesthetic period. It can be assessed by the following:\r\n
                                              \r\n \t
                                            1. Loss of response to stimulation including toe, ear, or tail pinch<\/li>\r\n \t
                                            2. Loose mandibular jaw tone<\/li>\r\n \t
                                            3. Absent blink reflex<\/li>\r\n \t
                                            4. Eye position \u2013 central eye position indicates depth of too deep or too light\r\n
                                                \r\n \t
                                              1. Non-ruminants \u2013 Eyes rotate rostroventrally<\/li>\r\n \t
                                              2. Ruminants \u2013 Eyes rotate ventrally and only sclera is seen<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                              3. Monitoring<\/strong>\r\n
                                                  \r\n \t
                                                1. Monitoring must be performed throughout the anesthetic episode with documentation at least every 15 minutes and until the animal is ambulatory. Examples of devices for monitoring can be found in Appendix D<\/strong><\/em>. \u00a0Do not leave animals unattended during the anesthetic period--remain within visual contact at all times to facilitate appropriate monitoring.\r\n
                                                    \r\n \t
                                                  1. Once the animal is in the recovery period, it is okay to step out of visual contact of the animal as long as:\r\n
                                                      \r\n \t
                                                    1. The animal is fully extubated with normal respirations (when applicable).<\/li>\r\n \t
                                                    2. The animal is fully secured so that if it becomes ambulatory it cannot escape the enclosure it is in (e.g. housing cage with lid, carrier with door closed, recovery cage).<\/li>\r\n \t
                                                    3. The animal continues to be monitored every 15 minutes until fully awake and ambulatory.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                    4. Minimal monitoring requirements include:<\/li>\r\n \t
                                                    5. Cardiovascular System:\r\n
                                                        \r\n \t
                                                      1. Heart rate or pulse rate must be monitored<\/em>\r\n
                                                          \r\n \t
                                                        1. Heart rate can be monitored by palpating the chest wall, placement of an esophageal stethoscope, or use of a standard stethoscope.<\/li>\r\n \t
                                                        2. Pulse rate can be monitored by palpating a pulse on the extremities or through monitoring equipment such as a doppler ultrasound, pulse oximetry or direct arterial blood pressure.<\/li>\r\n \t
                                                        3. An electrocardiogram can be used in conjunction with pulse oximetry or palpation to assess cardiac rhythm or detect cardiac dysrhythmias.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                        4. Peripheral perfusion must be assessed\u00a0in one of two<\/strong> methods<\/em>:\r\n
                                                            \r\n \t
                                                          1. Mucous Membranes: Assess capillary refill time (normal < 2 seconds) and\/or mucous membrane color (normal = pink).<\/li>\r\n \t
                                                          2. Pulse Oximetry: Non-invasive method to accurately measure peripheral capillary oxygen saturation (SpO2) along with pulse rate.\r\n
                                                              \r\n \t
                                                            1. Best if placed on the non-pigmented, non-haired regions of the body: tongue, ear, or commissures of the mouth.<\/li>\r\n \t
                                                            2. Ideal SpO2 > 95%\r\n
                                                                \r\n \t
                                                              1. SpO2 < 90% = hypoxia<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                              2. Blood pressure monitoring is highly recommended.\r\n
                                                                  \r\n \t
                                                                1. Invasive or noninvasive methods are available.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                2. Arterial Blood Gas\r\n
                                                                    \r\n \t
                                                                  1. For thoracic, cardiovascular, or neurologic procedures, serial arterial blood gas sampling is highly recommended.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                  2. Electrocardiograph (ECG)\r\n
                                                                      \r\n \t
                                                                    1. ECGs are recommended if dysrhythmias are expected secondary to surgical procedure or clinical condition.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                    2. Respiratory System:\r\n
                                                                        \r\n \t
                                                                      1. Respiratory rate must be monitored.<\/em>\r\n
                                                                          \r\n \t
                                                                        1. Respiratory rate can be assessed by visually counting chest wall inflations, utilizing a stethoscope, monitoring rebreathing bag movements, or by appropriate monitoring equipment such as mechanical ventilation bellows or capnography.<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                        2. Capnography (End-tidal CO2<\/sub> - ETCO2<\/sub>)\r\n
                                                                            \r\n \t
                                                                          1. Ideal range of ETCO2 <\/sub>for non-rodents under anesthesia is 35-50 mmHg.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                          2. Body Temperature:\r\n
                                                                              \r\n \t
                                                                            1. Body temperature must be monitored during anesthesia and recovery <\/em>to prevent serious changes from normal. Thermal support should be supplemented depending on species, procedure, and duration of procedure.\r\n
                                                                                \r\n \t
                                                                              1. Warming devices should provide gentle heat only (maximum of 102\u00b0F). When using a heating pad, an insulated pad or folded drape must be placed between the animal and the heat source.<\/li>\r\n \t
                                                                              2. AVOID commercial human electric heating pads, and heating lamps.<\/strong><\/span><\/li>\r\n \t
                                                                              3. See Appendix C<\/strong><\/em> for recommended warming devices for non-rodents<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>\r\n<\/li>\r\n \t
                                                                              4. Records: <\/strong>\r\n
                                                                                  \r\n \t
                                                                                1. Monitoring records must be kept for each animal undergoing any anesthetic procedure.<\/li>\r\n \t
                                                                                2. For animals undergoing an anesthetic procedure that is not a surgery, an anesthetic monitoring record is required that includes the date, individual animal information (weight, ID, etc.), the procedure being performed, documentation of all drugs administered including dose, route, and time frequency, and documentation of anesthetic monitoring for the duration of the anesthesia. This record can be kept in the lab but must be retrievable within four hours of request from veterinary or regulatory personnel.<\/li>\r\n \t
                                                                                3. Additional information on records for surgeries, or other documentation questions, please refer to the Guidelines on the Performance of Surgery in Non-Rodent Mammals<\/a> and the\u00a0Guidelines on Medical Records for Investigative Personnel<\/a>.<\/li>\r\n<\/ol>\r\n<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"2. Sedation Without General Anesthesia","legacy_section_text":"
                                                                                    \r\n \t
                                                                                  1. Cardiovascular, respiratory, and temperature monitoring guidelines should follow the recovery anesthesia monitoring guidelines.<\/li>\r\n \t
                                                                                  2. Oxygen should be supplemented by facemask. For heavy sedation, intubation equipment (laryngoscope and endotracheal tube) should be available in case protective airway reflexes are lost.<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"3. Non-Recovery Anesthesia Event","legacy_section_text":"
                                                                                      \r\n \t
                                                                                    1. Pre-Anesthetic Examination: <\/strong>A physical examination should be performed including heart rate and rhythm, mucous membrane color (normal = pink), capillary refill time (normal < 2 seconds), respiratory sounds and rate, and temperature.<\/li>\r\n \t
                                                                                    2. Records: <\/strong>Cardiovascular, respiratory, and body temperature monitoring guidelines should follow the recovery anesthesia monitoring guidelines.<\/li>\r\n<\/ol>","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"heading","legacy_heading":"Appendices","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"Appendix A: Rodent Anesthetic \/ Sedation Monitoring","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Rodent Surgical & Post Op Record (by Cage).pdf","url":"https:\/\/az.research.umich.edu\/animalcare\/forms\/rodent-surgical-post-op-record-cage","target":"_blank"},"legacy_import_link":true}]},{"legacy_section_type":"link_button","legacy_heading":"Appendix B: Non-Rodent Anesthetic \/ Sedation Monitoring","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Rodent Surgical & Post Op Record (by Cage)","url":"https:\/\/az.research.umich.edu\/animalcare\/forms\/rodent-surgery-and-post-operative-record-by-cage\/","target":"_blank"},"legacy_import_link":true}]},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"Appendix B: Non-Rodent Anesthetic \/ Sedation Monitoring","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Non-Rodent Mammal Intra-Operative Monitoring Form.pdf","url":"https:\/\/az.research.umich.edu\/animalcare\/forms\/non-rodent-mammal-intra-operative-monitoring-form","target":"_blank"},"legacy_import_link":true}]},{"legacy_section_type":"link_button","legacy_heading":"Appendix C: Heating \/ Warming Devices","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Non-Rodent Mammal Intra-Operative Monitoring Form","url":"https:\/\/az.research.umich.edu\/animalcare\/forms\/non-rodent-mammal-intra-operative-monitoring-form","target":"_blank"},"legacy_import_link":true}]},{"legacy_section_type":"text_area_with_subheading","legacy_heading":"","legacy_subheading":"Appendix C: Heating \/ Warming Devices","legacy_section_text":"","legacy_media_position":"media-full","legacy_media_file":3174,"legacy_media_url":"https:\/\/az.research.umich.edu\/sites\/default\/files\/media\/embedded\/Warming%20Devices.pdf","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"link_button","legacy_heading":"Appendix D: Monitoring Devices","legacy_subheading":"","legacy_section_text":"","legacy_media_position":"","legacy_media_file":"","legacy_media_url":"","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Heating \/ Warming 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Devices","legacy_section_text":"","legacy_media_position":"media-full","legacy_media_file":3175,"legacy_media_url":"https:\/\/az.research.umich.edu\/sites\/default\/files\/media\/embedded\/Monitoring%20Devices.pdf","legacy_glossary_term":"","legacy_glossary_nids":"","legacy_resource":"","legacy_resource_nids":"","legacy_buttons":null},{"legacy_section_type":"link_button","legacy_heading":"","legacy_subheading":"","legacy_section_text":"","legacy_media_position":false,"legacy_media_file":null,"legacy_media_url":"","legacy_glossary_term":null,"legacy_glossary_nids":"","legacy_resource":null,"legacy_resource_nids":"","legacy_buttons":[{"legacy_button":{"title":"Monitoring Devices","url":"https:\/\/az.research.umich.edu\/animalcare\/wp-content\/uploads\/sites\/2\/2025\/01\/Appendix-D-Monitoring-Devices-Anesthesia-and-Sedation-Monitoring-Guidelines.pdf","target":""},"legacy_import_link":true}]}],"update_notice_type":[51,53,54],"update_notice_start":"2025-10-24 21:00:00","update_notice_end":"2026-01-16 21:00:00","update_notice_text_blocks":[{"update_notice_text":"

                                                                                      Summary of Changes<\/strong><\/span><\/h3>\r\n