Research activities may involve the administration of hazardous substances to laboratory animals. If not contained properly, these activities can negatively impact the health of research and animal care personnel as well as other animals. This document outlines procedures to be utilized by personnel working with animals exposed to hazardous substances in ABSL-2 containment rooms (not including radioactive materials, see Related Documents section). Some procedures described in this SOP may not be applicable for non-rodent species, contact ULAM husbandry supervisors for further information. Extra precautions must be taken at the time of agent administration due to the increased potential for human exposure. Individuals who may be at an increased risk or susceptibility to a hazardous substance must be identified through Environmental Health & Safety's (EHS) medical surveillance process (e.g., pregnant women, immune compromised individuals). This SOP has been reviewed and approved by EHS with full consideration of all regulations. If further information is needed that is not found in this SOP, contact EHS. Any deviations from this SOP will need to be approved by EHS.
To describe the procedures for classifying animals that are single housed and labeling cages appropriately. All single housed animals on campus must be identified with the reason they are housed singly.
This policy of the University of Michigan (U-M) describes the information required by the Institutional Animal Care and Use Committee (IACUC) to address the need to account for animals produced through in-house breeding.
The Unit for Laboratory Animal Medicine (ULAM) has developed a policy by which the staff of a research laboratory can feed and/or water the rodents used in their research project(s), and thus not use ULAM husbandry for these services.