Ceding to an Independent (i.e., commercial IRB) under an existing Master Service Agreement.
U-M maintains Master Service Agreements with Advarra, Western IRB (WCG or WIRB), Ethical and Independent IRB (E&I), and NCI CIRB. No advance notification is necessary to initiate ceding of IRB review to these organizations. Complete the Ceding Application in eResearch.
U-M research teams must complete the "Request Review by a Non-UM IRB" (Ceding) Application within eResearch to receive an Acknowledgement letter and complete the independent IRBs application. Study teams must receive the U-M Acknowledgement letter and the independent IRB approval notice before beginning any research related activities.
Ceding under the SMART IRB Agreement (e.g., ceding to an academic IRB)
Ceding to an external (academic) IRB under the SMART IRB agreement requires submission of the eResearch ceding application. Also, provide SMART IRB Letter of Acknowledgement and/or the local context form from the external IRB. IRBMED will assess the appropriateness of ceding to this IRB for the designated study. Unless mandated by policy, the IRBMED cannot guarantee its willingness to rely on an external IRB.
Further information for institutions participating in the SMART IRB agreement:
RES_IRBMED_SMART IRB GUIDANCE COMPANION PIECE.DOCX
Ceding under No Prior Agreement
Submit an eResearch ceding application for IRBMED to consider a request to cede outside of a Master Services Agreement or SMART IRB agreement. These ceding requests will be assessed on a study-specific basis.