{"id":388,"date":"2018-05-29T11:24:47","date_gmt":"2018-05-29T11:24:47","guid":{"rendered":"https:\/\/az.research.umich.edu\/medschool\/glossary\/medschool-glossary-investigational\/"},"modified":"2024-11-19T22:29:12","modified_gmt":"2024-11-19T22:29:12","slug":"investigational","status":"publish","type":"glossary","link":"https:\/\/az.research.umich.edu\/medschool\/glossary\/investigational\/","title":{"rendered":"Investigational"},"template":"","class_list":["post-388","glossary","type-glossary","status-publish","hentry"],"acf":{"glossary_term_description":"<p>Clinical investigation means any experiment in which a test article, even an approved drug, is administered or dispensed to, or used involving, one or more human subjects. (FDA) The use of a marketed drug in the course of medical practice that is outside the label indications (\"off-label\" use or innovative care) does not in and of itself constitute investigational use of a drug, unless that use is part of an experiment or systematic investigation meeting the criteria for&nbsp;<a class=\"gtip\" href=\"\/medschool\/glossary\/human-subject\">human subject&nbsp;research.<\/a><\/p>","glossary_related_terms":"","legacy_glossary_node_id":621,"legacy_related_terms":""},"_links":{"self":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/glossary\/388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/types\/glossary"}],"wp:attachment":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/media?parent=388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}