{"id":499,"date":"2018-05-30T10:50:41","date_gmt":"2018-05-30T10:50:41","guid":{"rendered":"https:\/\/az.research.umich.edu\/medschool\/glossary\/medschool-glossary-serious-adverse-event-sae-or-serious-adverse-drug-reaction-serious-adr\/"},"modified":"2024-11-19T22:29:19","modified_gmt":"2024-11-19T22:29:19","slug":"serious-adverse-event-sae-or-serious-adverse-drug-reaction-serious-adr","status":"publish","type":"glossary","link":"https:\/\/az.research.umich.edu\/medschool\/glossary\/serious-adverse-event-sae-or-serious-adverse-drug-reaction-serious-adr\/","title":{"rendered":"Serious Adverse Event (SAE) or Serious Adverse Drug Reaction (Serious ADR)"},"template":"","class_list":["post-499","glossary","type-glossary","status-publish","hentry"],"acf":{"glossary_term_description":"<p>Any adverse experience occurring at any dose or level of participation that results in any of the following outcomes:<\/p>\n\n<ul>\n\t<li>Results in death,<\/li>\n\t<li>Is life-threatening<\/li>\n\t<li>Requires inpatient hospitalization or prolongation of existing hospitalization,<\/li>\n\t<li>Results in persistent or significant disability\/incapacity, or<\/li>\n\t<li>Is a congenital anomaly\/birth defect.<\/li>\n\t<li>An unexpected result of therapy or other intervention that is severe, life threatening, or fatal, corresponding to grades III, IV, or V using NCI\/CTC Common Toxicity Criteria.<\/li>\n<\/ul>","glossary_related_terms":"","legacy_glossary_node_id":736,"legacy_related_terms":""},"_links":{"self":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/glossary\/499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/types\/glossary"}],"wp:attachment":[{"href":"https:\/\/az.research.umich.edu\/medschool\/wp-json\/wp\/v2\/media?parent=499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}